Edinburgh Medical School
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One Health is the approach underpinning the research done at the Edinburgh Medical School. The modern challenges that face not only the UK but the world in terms of the rise of chronic disease, the shifts in populations and the challenges presented by a population which is living much longer are common and the mechanisms underpinning them are common. The aim of the School is to bring the right individuals together to catalyse and create the opportunities to really develop exciting and cutting edge clinical and non-clinical research that makes a difference to people’s lives.
Image: CC-BY Mikhael, S dx.doi.org/10.7488/ds/1576
Sub-communities within this community
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Molecular, Genetic and Population Health Sciences
Institute of Genetics and Molecular Medicine and Usher Institute
Collections in this community
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John West's Research Group
Corneal epithelium research
Recent Submissions
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Systematic Review of the Literature on Definitions and Characterisation of MS Lesions
While inspecting the brain magnetic resonance imaging (MRI) scans from a sample of Multiple Sclerosis (MS) patients, blind to any clinical, cognitive and demographic information, it caught our attention the presence of ... -
Brain Network Measures and Spatial Lesion Distribution in a Sample of 47 Patients with Systemic Lupus Erythematosus (SLE)
This dataset corresponds to a research on network organisation of brain structural connectivity in systemic lupus erythematosus (SLE) and its putative association with lesion distribution and disease indicators. White ... -
Insights into the genetic basis of retinal detachment
Dataset of genome-wide association meta-analysis summary statistics associated with the publication “Insights into the genetic basis of retinal detachment” available as a preprint at BiorXiv: doi: https://doi.org/10.1101/581165. ... -
Generation Scotland Age x Sex Epigenome Wide Association Study Summary Statistics
This directory contains full summary statistics for the following EWAS studies in the Generation Scotland cohort. Epigenome-wide autosomal sites associated with chronological age with concordant effect sizes in the ... -
Resolving the fibrotic niche of human liver cirrhosis at single-cell level - Seurat RData object
We profile the transcriptomes of non-parenchymal cell types present in healthy and cirrhotic human liver. In particular, we uncover a novel scar-associated TREM2+CD9+ macrophage subpopulation, which expands in liver fibrosis, ... -
Fan cells in layer 2 of lateral entorhinal cortex are critical for episodic-like memory
Episodic memory requires different types of information to be bound together to generate representations of experiences. The lateral entorhinal cortex (LEC) and hippocampus are required for episodic-like memory in rodents. ... -
Interleukin-1 receptor antagonist treatment in acute ischaemic stroke does not alter systemic markers of anti-microbial defence
Background: Blockade of the cytokine interleukin-1 (IL-1) with IL-1 receptor antagonist (IL-1Ra) is a candidate treatment for stroke entering phase II/III trials, which acts by inhibiting harmful inflammatory responses. ... -
aNMJ-morph macro
It is recommended that users of the aNMJ-morph macro are familiar with the original NMJ-morph workflow in a practical setting; please refer to the following publication for background details: "NMJ-morph reveals principal ... -
Dataset 2 pertaining to the publication "Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants"
The Generation Scotland: Scottish Family Health Study (GS:SFHS) is a family-based population cohort with DNA, biological samples, socio-demographic, psychological and clinical data from ~24,000 adult volunteers across ... -
Image analysis macros for array tomography
The MATLAB and image J scripts provided here were used to analyse array tomography image stacks in the study "Reducing tau ameliorates behavioural and transcriptional deficits in a novel model of Alzheimer's disease" by ... -
Circuits! - Demonstrating the use of optical fibres in biomedical sciences
The Circuits! - project, funded through the The Royal Academy of Engineering Ingenious Grant (ING1617/11/114), demonstrates how research at the intersection of physics, engineering, biology, and medicine can be presented ... -
Generation Scotland Survey Monkey data
Generation Scotland (GS) conducted a recontact survey on ~7,000 participants who could be contacted by email. The survey used Survey Monkey Inc. to understand GS participant opinions on health research. A total of 2,316 ... -
SUPERSEDED - Interleukin-1 receptor antagonist treatment in acute ischaemic stroke does not alter systemic markers of anti-microbial defence
## This item has been replaced by the one which can be found at https://doi.org/10.7488/ds/2626 ## Background: Blockade of the cytokine interleukin-1 (IL-1) with IL-1 receptor antagonist (IL-1Ra) is a candidate treatment ... -
SUPERSEDED - Interleukin-1 receptor antagonist treatment in acute ischaemic stroke does not alter systemic markers of anti-microbial defence
## This item has been replaced by the one which can be found at http://hdl.handle.net/10283/3354 ## Full datasets for all figures in the manuscript "Interleukin-1 receptor antagonist treatment in acute ischaemic stroke ... -
Data and code for: High fidelity fibre-based physiological sensing deep in tissue
Physiological sensing deep in tissue, remains a clinical challenge. Here a flexible miniaturised sensing optrode providing a platform to perform minimally invasive in vivo in situ measurements is reported. Silica microspheres ... -
SUPERSEDED - Supplementary Figures: Interleukin-1 receptor antagonist treatment in acute ischaemic stroke does not alter systemic markers of anti-microbial defence
## This item has been replaced by the one which can be found at https://doi.org/10.7488/ds/2626 ## Supplementary Figures from the manuscript "Interleukin-1 receptor antagonist treatment in acute ischaemic stroke does not ... -
Data for re-evaluation of the causes of variation among mouse aggregation chimaeras
The data are numerical data used to produce Figs. 2 & 5, Supplementary Figs. S3–S6 and Supplementary Table S2 in a manuscript entitled “Re-evaluation of the causes of variation among mouse aggregation chimaeras” by West ... -
Supplementary data to "Ligand binding site structure shapes folding, assembly and degradation of homomeric protein complexes" by G. Abrusan and J.A. Marsh
The structure of ligand binding sites has profound consequences for the evolution of function of protein complexes, particularly in homomers. Homomers with multichain binding sites (MBS) are characterized with more conserved ... -
Burden of RSV-associated ALRI in Children with Congenital Heart Disease
Introduction: Respiratory syncytial virus (RSV) is the most common viral cause of Acute Lower Respiratory Infections (ALRI) with significant childhood morbidity and mortality worldwide, especially among those with underlying ... -
Global patterns in monthly activity of influenza virus, respiratory syncytial virus, parainfluenza virus, and metapneumovirus: a systematic analysis
Background: Influenza virus (IFV), respiratory syncytial virus (RSV), parainfluenza virus (PIV), and metapneumovirus (MPV) are the most common viruses associated with acute lower respiratory infections in young children ...
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