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Depositordc.contributorAdams, Mark
Funderdc.contributor.otherWellcome Trusten_UK
Spatial Coveragedc.coverage.spatialScotlanden_UK
Spatial Coveragedc.coverage.spatialUKen
Spatial Coveragedc.coverage.spatialUNITED KINGDOMen
Data Creatordc.creatorWigmore, Ella
Data Creatordc.creatorHafferty, Jonathan
Data Creatordc.creatorHall, Lynsey
Data Creatordc.creatorHoward, David
Data Creatordc.creatorClarke, Toni-Kim
Data Creatordc.creatorFabbri, Chiara
Data Creatordc.creatorLewis, Cathryn
Data Creatordc.creatorUher, Rudolf
Data Creatordc.creatorNavrady, Lauren
Data Creatordc.creatorAdams, Mark
Data Creatordc.creatorZeng, Yanni
Data Creatordc.creatorCampbell, Archie
Data Creatordc.creatorGibson, Jude
Data Creatordc.creatorThomson, Pippa
Data Creatordc.creatorHayward, Caroline
Data Creatordc.creatorSmith, Blair
Data Creatordc.creatorHocking, Lynne
Data Creatordc.creatorPadmanabhan, Sandosh
Data Creatordc.creatorDeary, Ian
Data Creatordc.creatorPorteous, David
Data Creatordc.creatorMors, Ole
Data Creatordc.creatorMattheisen, Manuel
Data Creatordc.creatorNicodemus, Kristin
Data Creatordc.creatorMcIntosh, Andrew
Date Accessioneddc.date.accessioned2020-03-31T10:07:33Z
Date Availabledc.date.available2020-03-31T10:07:33Z
Citationdc.identifier.citationWigmore, Ella; Hafferty, Jonathan; Hall, Lynsey; Howard, David; Clarke, Toni-Kim; Fabbri, Chiara; Lewis, Cathryn; Uher, Rudolf; Navrady, Lauren; Adams, Mark; Zeng, Yanni; Campbell, Archie; Gibson, Jude; Thomson, Pippa; Hayward, Caroline; Smith, Blair; Hocking, Lynne; Padmanabhan, Sandosh; Deary, Ian; Porteous, David; Mors, Ole; Mattheisen, Manuel; Nicodemus, Kristin; McIntosh, Andrew. (2020). Genome-wide association summary statistics of antidepressant treatment resistance meta-analysis, [dataset]. University of Edinurgh. Centre for Clinical Brain Sciences. Department of Psychiatry. https://doi.org/10.7488/ds/2791.en
Persistent Identifierdc.identifier.urihttp://hdl.handle.net/10283/3597
Persistent Identifierdc.identifier.urihttps://doi.org/10.7488/ds/2791
Dataset Description (abstract)dc.description.abstractData from Wigmore et al "Genome-wide association study of antidepressant treatment resistance in a population-based cohort using health service prescription data and meta-analysis with GENDEP". The Pharmacogenomics Journal 20, 329–341 (2020) DOI:10.1038/s41397-019-0067-3 This dataset consists of two sets of GWAS summary statistics: - case-control analysis of treatment resistance phenotype in the Generation Scotland and GENDEP samples (inverse variance weighted meta-analysis). Cases = 358, Controls = 3855. - quantitative stages of resistance phenotype in Generation Scotland. N = 3452.en_UK
Dataset Description (TOC)dc.description.tableofcontentsFile: TRD_meta.Wigmore2020.txt.gz Description: Meta-analysis of Generation Scotland and GENDEP Columns: - CHR: chromosome - SNP: marker RSID - BP: base-pair position - A1: effect allele - A2: non-effect allele - Freq1: average frequency of A1 - FreqSE: standard error of frequency - logOR: effect of A1 as log Odds Ratio - logOR_SE: standard error of the effect - P: p-value - Direction: direction of effect from each study (order: GENDEP, GenScot) - HetISq, HetChiSq, HetDf, HetPVal: heterogeneity statistics File: TRD_Stages.Wigmore2020.txt.gz Description: Stage of resistance in Generation Scotland Columns: - CHR: chromsome - SNP: marker RSID - BP: base-pair position - A1: effect allele - A2: non-effect allele - Freq: frequency of A1 - beta: effect of A1 - se: standard error of effect - P: p-valueen_UK
Languagedc.language.isoengen_UK
Publisherdc.publisherUniversity of Edinurgh. Centre for Clinical Brain Sciences. Department of Psychiatryen_UK
Relation (Is Referenced By)dc.relation.isreferencedbyhttps://doi.org/10.1038/s41397-019-0067-3en_UK
Rightsdc.rightsCreative Commons Attribution 4.0 International Public Licenseen
Subjectdc.subjectdepressionen_UK
Subjectdc.subjectantidepressanten_UK
Subjectdc.subjectelectronic health recordsen_UK
Subject Classificationdc.subject.classificationMedicine and Dentistryen_UK
Titledc.titleGenome-wide association summary statistics of antidepressant treatment resistance meta-analysisen_UK
Alternative Titledc.title.alternativeGenome-wide association study of antidepressant treatment resistance in a population-based cohort using health service prescription data and meta-analysis with GENDEPen_UK
Typedc.typedataseten_UK

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