The Usher Institute is a high-energy, interdisciplinary environment dedicated to improving the health of individuals and populations locally and globally through research, innovation, knowledge exchange and education.

The Usher Institute sits within the Edinburgh Medical School. It has 4 core research centres, hosts the Edinburgh Clinical Trials Unit, and is a delivery hub within the Data-Driven Innovation Programme of the Edinburgh and South East Scotland City Region Deal

www.ed.ac.uk/usher

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Recent Submissions

  • SAIL dementia e-cohort (SAIL-DeC) 

    Wilkinson, Tim; Schnier, Christian; Akbari, Ashley; Orton, Chris; Sleegers, Kristel; Gallacher, John; Lyons, Ronan A; Sudlow, Cathie LM
    These files contain details on the creation of the Secure Anonymised Information Linkage (SAIL) databank dementia e-cohort (SAIL-DeC).
  • Genomics of 1 million parent lifespans implicates novel pathways and common diseases and distinguishes survival chances 

    Timmers, Paul R H J; Läll, Kristi; Fischer, Krista; Ning, Zheng; Feng, Xiao; Bretherick, Andrew; Clark, David W; Shen, Xia; Esko, Tōnu; Kutalik, Zoltán; Wilson, James F; Joshi, Peter K
    We use a genome-wide association of 1 million parental lifespans of genotyped subjects and data on mortality risk factors to validate previously unreplicated findings near CDKN2B-AS1, ATXN2/BRAP, FURIN/FES, ZW10, PSORS1C3, ...
  • Epidemiological characteristics of human-infective RNA viruses 

    Woolhouse, Mark; Brierley, Liam
    RNA viruses are a major threat to human health. Here, based on extensive literature searches carried out over a period of 18 years, we provide a catalogue of all 214 known human-infective RNA virus species. We link these ...
  • SUPERSEDED - Epidemiological characteristics of human-infective RNA viruses 

    Woolhouse, Mark; Brierley, Liam
    ## This data item has been replaced by the one which can be found at https://doi.org/10.7488/ds/2265 . ## RNA viruses are a major threat to human health. Here, based on extensive literature searches carried out over a ...
  • SUPERSEDED - Epidemiological characteristics of human-infective RNA viruses 

    Woolhouse, Mark; Brierley, Liam
    ## This item has been superseded by the one which can be found at https://doi.org/10.7488/ds/2265 . ## RNA viruses are a major threat to human health. Here, based on extensive literature searches carried out over a period ...
  • Data extraction sheet for the systematic review of VARI-PD 

    Li, You
    Pneumococcal disease (PD) is a major cause of communicable disease burden globally. Evidence from animal and in vitro studies suggest viral acute respiratory infection (VARI) can predispose to pneumococcal infection. ...
  • Data supporting Rubio et al on exacerbations of COPD 

    Rubio, Noah; Parker, Richard A; Drost, Ellen M; Pinnock, Hilary; Weir, Christopher J; Hanley, Janet; Mantoani, Leandro C; MacNee, William; McKinstry, Brian; Rabinovich, Roberto A; McCloughan, Lucy
    Please see the publication Rubio et al. ('Home monitoring of breathing rate in people with Chronic Obstructive Pulmonary Disease: observational study of feasibility, acceptability and change after exacerbation' International ...
  • SUPERSEDED - Data supporting Rubio et al on exacerbations of COPD 

    Rubio, Noah; Parker, Richard A; Drost, Ellen M; Pinnock, Hilary; Weir, Christopher J; Hanley, Janet; Mantoani, Leandro C; MacNee, William; McKinstry, Brian; Rabinovich, Roberto A; McCloughan, Lucy
    ## This dataset has been replaced by the one at https://doi.org/10.7488/ds/1981 . ##
  • The third International Stroke Trial (IST-3) 

    Sandercock, P; Wardlaw, Joanna; Lindley, R; Cohen, G; Whiteley, W
    The IST-3 trial is a large-scale randomised controlled trial of intravenous thrombolytic therapy of the drug Alteplase for patients with acute ischaemic stroke. The dataset includes a number of files describing the IST-3 ...
  • International Stroke Trial database (version 2) 

    Sandercock, Peter; Niewada, Maciej; Czlonkowska, Anna (University of Edinburgh. Department of Clinical Neurosciences, 2011-11-02)
    The International Stroke Trial (IST) was one the biggest randomised trials in acute stroke. Methods: Available data on variables assessed at randomisation, at the early outcome point (14-days after randomisation or prior ...
  • International Stroke Trial database (superseded) 

    Sandercock, Peter; Niewada, Maciej; Czlonkowska, Anna (University of Edinburgh. Department of Clinical Neurosciences, 2010-09-24)
    The International Stroke Trial (IST) was one the biggest randomised trials in acute stroke. Methods: Available data on variables assessed at randomisation, at the early outcome point (14-days after randomisation or prior ...