Fibre-based Fluorescence Lung Imaging
Lung diseases, such as asthma, acute respiratory infections, tuberculosis, lung cancer, and chronic obstructive pulmonary disease (COPD), are a global concern. More than one billion people suffer from either acute or chronic respiratory conditions worldwide. Better understanding of lung disease is crucial to reducing morbidity and mortality. Fluorescence-based optical endomicroscopy (OEM) systems, enabled with fibre bundles, have stimulated interest within this area because they provide a low cost and minimally invasive solution for high resolution imaging and measurements in vivo, in situ.
Image: Tanner, Michael G. (2019). Data and code for: High fidelity fibre-based physiological sensing deep in tissue, [dataset]. University of Edinburgh. https://datashare.is.ed.ac.uk/handle/10283/3325
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The Circuits! - project, funded through the The Royal Academy of Engineering Ingenious Grant (ING1617/11/114), demonstrates how research at the intersection of physics, engineering, biology, and medicine can be presented ...
Physiological sensing deep in tissue, remains a clinical challenge. Here a flexible miniaturised sensing optrode providing a platform to perform minimally invasive in vivo in situ measurements is reported. Silica microspheres ...
Data and Code for "Fibre-based Spectral Ratio Endomicroscopy for Contrast Enhancement of Bacterial Imaging and Pulmonary Autofluorescence" Fibre-based optical endomicroscopy (OEM) permits high resolution fluorescence microscopy in endoscopically accessible tissues. Fibred OEM has the potential to visualise pathologies targeted with fluorescent imaging probes ...