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Depositordc.contributorParker, Helen E.
Funderdc.contributor.otherEPSRC - Engineering and Physical Sciences Research Councilen_UK
Funderdc.contributor.otherWarren's Wish (Registered Scottish charity number SC 045290)en_UK
Data Creatordc.creatorTanner, Michael G
Data Creatordc.creatorParker, Helen E
Data Creatordc.creatorStone, James M
Data Creatordc.creatorThomson, Robert R
Data Creatordc.creatorMarshall, Adam D L
Data Creatordc.creatorChoudhary, Tushar R
Data Creatordc.creatorDhaliwal, Kevin
Citationdc.identifier.citationTanner, Michael G; Parker, Helen E; Stone, James M; Thomson, Robert R; Marshall, Adam D L; Choudhary, Tushar R; Dhaliwal, Kevin. (2019). Data and Code for "Fibre-based Spectral Ratio Endomicroscopy for Contrast Enhancement of Bacterial Imaging and Pulmonary Autofluorescence", [dataset]. University of Edinburgh. Queen's Medical Research Institute.
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Dataset Description (abstract)dc.description.abstractFibre-based optical endomicroscopy (OEM) permits high resolution fluorescence microscopy in endoscopically accessible tissues. Fibred OEM has the potential to visualise pathologies targeted with fluorescent imaging probes and provide an in vivo in situ molecular pathology platform to augment disease understanding, diagnosis and stratification. Here we present an inexpensive widefield ratiometric fibred OEM system capable of enhancing the contrast between similar spectra of pathologically relevant fluorescent signals without the burden of complex spectral unmixing. As an exemplar, we demonstrate the potential of the platform to detect fluorescently labelled Gram-negative bacteria in the challenging environment of highly autofluorescent lung tissue in whole ex vivo human lungs.en_UK
Dataset Description (TOC)dc.description.tableofcontentsReadme.txten_UK
Publisherdc.publisherUniversity of Edinburgh. Queen's Medical Research Instituteen_UK
Relation (Is Referenced By)dc.relation.isreferencedby
Relation (Is Referenced By)dc.relation.isreferencedbyHelen E. Parker, James M. Stone, Adam D. L. Marshall, Tushar R. Choudhary, Robert R. Thomson, Kevin Dhaliwal, and Michael G. Tanner, "Fibre-based spectral ratio endomicroscopy for contrast enhancement of bacterial imaging and pulmonary autofluorescence," Biomed. Opt. Express 10, 1856-1869 (2019)
Rightsdc.rightsCreative Commons Attribution 4.0 International Public Licenseen
Subjectdc.subjectSpectral imagingen_UK
Subjectdc.subjectFibre based imagingen_UK
Subjectdc.subjectFluorescence imagingen_UK
Subjectdc.subjectLung imagingen_UK
Subjectdc.subjectImage processingen_UK
Subject Classificationdc.subject.classificationPhysical Sciences::Medical Physicsen_UK
Titledc.titleData and Code for "Fibre-based Spectral Ratio Endomicroscopy for Contrast Enhancement of Bacterial Imaging and Pulmonary Autofluorescence"en_UK

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