Now showing items 1-6 of 6
"Increased Abundance of M cells in the Gut Epithelium Dramatically Enhances Oral Prion Disease Susceptibility"
Data supporting Donaldson et al "Increased Abundance of M cells in the Gut Epithelium Dramatically Enhances Oral Prion Disease Susceptibility" (In Submission).
TMT generated proteomic identification and quantification of muscle and NMJ enriched fractions in mice and humans
The neuromuscular junction (NMJ) plays a fundamental role in transferring information from lower motor neurons to skeletal muscle to generate movement. It is also an experimentally-accessible model synapse routinely studied ...
Investigating early cellular and molecular responses to misfolded protein
PMDs such as AD, PD, HD and TSE are associated with the accumulation of abnormally folded proteins. However, the mechanisms involving seeding, processing and degradation of these rogue proteins are poorly understood. In ...
Open prediction of polysaccharide utilisation loci (PUL) in 5414 public Bacteroidetes genomes using PULpy
Polysaccharide utilisation loci (PUL) are regions within the genomes of Bacteroidetes that encode all the necessary machinery for the cleavage of particular carbohydrates. Prediction of PUL from genomic data alone involves ...
Proteomic profiling of primate synapses during normal healthy ageing
Normal mammalian brain ageing is characterised by the selective loss of discrete populations of dendritic spines and synapses, particularly affecting neuroanatomical regions such as the hippocampus. Although previous ...
Proteomic analysis for peripherally accessible biomarkers in Neuronal Ceroid Lipofuscinosis (NCL)
iTRAQ and Label free Proteomic data generated from Skeletal muscle of CLN3 and PPT1 murine models of Batten disease.