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RNA composition metrics
Mutating RNA virus genomes to alter codon pair (CP) frequencies and reduce translation efficiency has been advocated as a method to generate safe, attenuated virus vaccines. However, selection for disfavoured CPs leads to ...
"Increased Abundance of M cells in the Gut Epithelium Dramatically Enhances Oral Prion Disease Susceptibility"
Data supporting Donaldson et al "Increased Abundance of M cells in the Gut Epithelium Dramatically Enhances Oral Prion Disease Susceptibility" (In Submission).
TMT generated proteomic identification and quantification of muscle and NMJ enriched fractions in mice and humans
The neuromuscular junction (NMJ) plays a fundamental role in transferring information from lower motor neurons to skeletal muscle to generate movement. It is also an experimentally-accessible model synapse routinely studied ...
Proteomic analysis for peripherally accessible biomarkers in Neuronal Ceroid Lipofuscinosis (NCL)
iTRAQ and Label free Proteomic data generated from Skeletal muscle of CLN3 and PPT1 murine models of Batten disease.