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Depositordc.contributorWest, John
Funderdc.contributor.otherWellcome Trusten_UK
Data Creatordc.creatorFlockhart, Jean H.
Data Creatordc.creatorTang, Pin-Chi
Data Creatordc.creatorMacKay, Gillian E.
Data Creatordc.creatorKeighren, Margaret A.
Data Creatordc.creatorKissenpfennig, Adrien
Data Creatordc.creatorWilson, Linda
Data Creatordc.creatorPratt, Thomas
Data Creatordc.creatorMason, John O.
Data Creatordc.creatorPrice, David J.
Data Creatordc.creatorWest, John D.
Date Accessioneddc.date.accessioned2017-06-06T16:27:21Z
Date Availabledc.date.available2017-06-06T16:27:21Z
Citationdc.identifier.citationFlockhart, Jean H.; Tang, Pin-Chi; MacKay, Gillian E.; Keighren, Margaret A.; Kissenpfennig, Adrien; Wilson, Linda; Pratt, Thomas; Mason, John O.; Price, David J.; West, John D.. (2017). Data on the composition of four balanced and four unbalanced series of E12.5 fetal mouse chimaeras, [dataset]. University of Edinburgh. Edinburgh Medical School. https://doi.org/10.7488/ds/2056.en
Persistent Identifierdc.identifier.urihttp://hdl.handle.net/10283/2723
Persistent Identifierdc.identifier.urihttps://doi.org/10.7488/ds/2056
Dataset Description (abstract)dc.description.abstractThis is numerical data used to compare the composition of different series of fetal mouse chimaeras. Eight series of chimaeras were created as matched pairs in four studies and the composition of each chimaeric conceptus was evaluated by electrophoresis of glucose phosphate isomerase (GPI) markers. These data show that BALB/c embryos tend to contribute poorly to mouse chimaeras [references 1, 3, 4] and this appears to be mediated, in part, by a maternal effect [reference 2]. 1. West, J.D., Flockhart, J.H., 1994. Genotypically unbalanced diploid ↔diploid foetal mouse chimaeras: possible relevance to human confined mosaicism. Genet Res 63, 87-99. DOI: https://doi.org/10.1017/S0016672300032195 2. West, J.D., Flockhart, J.H., Kissenpfennig, A., 1995. A maternal genetic effect on the composition of mouse aggregation chimaeras. Genet Res 65, 29-40. DOI: https://doi.org/10.1017/S0016672300032985 3. Tang, P.-C. & West, J.D., 2001. Size regulation does not cause the composition of mouse chimaeras to become unbalanced. Int. J. Dev. Biol. 45, 583-590. 4. MacKay, G.E., Keighren, M.A., Wilson, L., Pratt, T., Flockhart, J.H., Mason, J.O., Price, D.J., West, J.D., 2005. Evaluation of the mouse TgTP6.3 tauGFP transgene as a lineage marker in chimeras. J. Anat. 206, 79-92. DOI: 10.1111/j.0021-8782.2005.00370.xen_UK
Dataset Description (TOC)dc.description.tableofcontents1 Excel Workbook (with 4 spreadsheets): Data from 8 series of fetal mouse chimaeras. Spreadsheet 1: Chimaera Series XM and XR. (From West & Flockhart, 1994). Spreadsheet 2: Chimaera Series XP and XN. (From West et al 1995). Spreadsheet 3: Chimaera Series PCT-V and PCT-VI. (From Tang & West 2001). Spreadsheet 4: Chimaera Series GMA and GMB. (From MacKay et al 2005). 1 “Read Me” file (pdf format). 1 “Read Me” file (docx format).en_UK
Languagedc.language.isoengen_UK
Publisherdc.publisherUniversity of Edinburgh. Edinburgh Medical Schoolen_UK
Relation (Is Referenced By)dc.relation.isreferencedbyhttps://doi.org/10.1017/S0016672300032195en_UK
Relation (Is Referenced By)dc.relation.isreferencedbyhttps://doi.org/10.1017/S0016672300032985en_UK
Relation (Is Referenced By)dc.relation.isreferencedbyTang, P.-C. & West, J.D., 2001. Size regulation does not cause the composition of mouse chimaeras to become unbalanced. Int. J. Dev. Biol. 45, 583-590.en_UK
Relation (Is Referenced By)dc.relation.isreferencedbyDOI: 10.1111/j.0021-8782.2005.00370.xen_UK
Rightsdc.rightsCreative Commons Attribution 4.0 International Public Licenseen
Subjectdc.subjectmouseen_UK
Subjectdc.subjectBALB/c strainen_UK
Subjectdc.subjectmouse chimaeraen_UK
Subjectdc.subjectmouse chimeraen_UK
Subjectdc.subjectunbalanced chimaeraen_UK
Subjectdc.subjectunbalanced chimeraen_UK
Subjectdc.subjectmaternal effecten_UK
Subjectdc.subjectglucose phosphate isomeraseen_UK
Subjectdc.subjectGPIen_UK
Subject Classificationdc.subject.classificationBiological Sciencesen_UK
Titledc.titleData on the composition of four balanced and four unbalanced series of E12.5 fetal mouse chimaerasen_UK
Typedc.typedataseten_UK

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