The School of Biological Sciences incorporates a number of discipline-based Research Institutes: Institute of Cell Biology, Institute of Evolutionary Biology, Institute of Immunology and Infection Research, Institute of Molecular Plant Sciences, Institute for Stem Cell Research, Institute of Structural and Molecular Biology.

The School participates in many interdisciplinary Research Centres such as SynthSys and the Centre for Translational & Chemical Biology.

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Recent Submissions

  • LIVE-PAINT Supporting Datasets 

    Oi, Curran; Horrocks, Mathew; Gidden, Zoe; Regan, Lynne
    We present LIVE-PAINT, a new approach to super-resolution fluorescent imaging inside live cells. In LIVE-PAINT only a short peptide sequence is fused to the protein being studied, unlike conventional super-resolution ...
  • The proteomic landscape of centromeric chromatin reveals an essential role for the Ctf19CCAN complex in meiotic kinetochore assembly 

    Borek, Weronika; Marston, Adele; Duro, Eris
    Dataset in support of manuscript "The proteomic landscape of centromeric chromatin reveals an essential role for the Ctf19CCAN complex in meiotic kinetochore assembly" in submission to Mol. Cell. The dataset comprises of ...
  • Comparative Genomics of Chlamydomonas 

    Craig, Rory
    Files for "Comparative genomics of Chlamydomonas" manuscript.
  • Rhizobox validation 

    Bontpart, Thibaut; Concha, Cristobal; Giuffrida, Valerio; Robertson, Ingrid; Admkie, Kassahun; Degefu, Tulu; Girma, Nigussie; Tesfaye, Kassahun; Haileselassie, Teklehaimanot; Fikre, Asnake; Fetene, Masresha; Tsaftaris, Sotirios; Doerner, Peter
    The dataset consists of code, CAD files, method descriptions and images.
  • LIVE-PAINT Supplementary Videos: Compressed versions 

    Oi, Curran; Horrocks, Mathew; Regan, Lynne
    Compressed versions of the files of Oi, Curran; Horrocks, Mathew; Regan, Lynne. (2020). LIVE-PAINT Supplementary Videos, [dataset]. University of Edinburgh. Quantitative Biology, Biochemistry and Biotechnology. ...
  • A General Workflow for Characterization of Nernstian Dyes and Their Effects on Bacterial Physiology 

    Mancini, Leonardo; Terradot, Guillaume; Tian, Tian; Pu, YingYing; Li, YingXing; Lo, Chien-Jung; Bai, Fan; Pilizota, Teuta
    The electrical membrane potential (Vm) is one of the components of the electrochemical potential of protons across the biological membrane (proton motive force), which powers many vital cellular processes. Because Vm also ...
  • LIVE-PAINT Supplementary Videos 

    Oi, Curran; Horrocks, Mathew; Regan, Lynne
    We present LIVE-PAINT, a new approach to super-resolution fluorescent imaging inside live cells. In LIVE-PAINT only a short peptide sequence is fused to the protein being studied, unlike conventional super-resolution ...
  • Peptide occurrences dataset from UniProt Feb 2018 

    Shave, Steven
    Peptide occurences at different lengths, found in UniProt Feb 2018 release (UniProtKB/Swiss-Prot 2018_02 - February 28, 2018). An output of the Leverhulme funded project: Understanding the biological ramifications of a ...
  • Peterson_data 

    Peterson, Karianne; Savill, Nick; Illius, Andrew
    Serological data from Peterson, K., Stegeman, A., Colenbrander, B., and Houwers, D. J. (2007). Comparative quantification of the lateral transmission of Maedi Visna virus in two flocks of sheep of different genetic ...
  • Houwers_data 

    Houwers, Dirk; Savill, Nick; Illius, Andrew
    Serological data from Houwers, D. J. and van der Molen, E. J. (1987). A five-year serological study of natural transmission of maedi-visna virus in a flock of sheep, completed with post mortem investigation. Journal of ...
  • Timeseries used in Zielinski et al. Strengths and Limitations of Period Estimation Methods 

    Zielinski, Tomasz; Millar, Andrew J
    Dataset contains timeseries data used for testing period analysis methods. The full details of the data are described in the actual paper, here there is only a short summary of methods generation. The synthetic test ...
  • Comparison of Escherichia coli surface attachment methods for single-cell microscopy 

    Wang, Yao-Kuan; Krasnopeeva, Ekaterina; Pilizota, Teuta; Lo, Chien-Jung
    See readme file. ## Funding ## This research was funded by Human Frontier Science Program Grant (RGP0041/2015) and the Ministry of Science and Technology, Republic of China under contract No. MOST-107-2112-M-008-025-MY3.
  • Host circadian clocks do not set the schedule for the within-host replication of malaria parasites 

    O'Donnell, Aidan; Prior, KF; Reece, Sarah E
    Circadian clocks coordinate organisms’ activities with daily cycles in their environment. Parasites are subject to daily rhythms in the within-host environment, resulting from clock-control of host behaviours and physiologies, ...
  • Estimating numbers of intracellular molecules through analysing fluctuations in photobleaching 

    Bakker, Elco; Swain, P
    The impact of fluorescence microscopy has been limited by the difficulties of expressing measurements of fluorescent proteins in numbers of molecules. Absolute numbers enable the integration of results from different ...
  • Data from: Adaptive phenotypic plasticity in malaria parasites is not constrained by previous responses to environmental change. 

    Birget, Philip LG; Schneider, Petra; O'Donnell, Aidan J; Reece, Sarah E
    Infection dynamics data for P. chabaudi parasites in treatment groups that include parasites in mice treated with 30mg/kg phenylhydrazine (“PHZ”), parasites in untreated mice (“Control”), or parasites currently in untreated ...
  • Single-cell bacterial electrophysiology reveals mechanisms of stress induced damage - additional data (Figures 2D, 3D, 4D) 

    Pilizota, Teuta; Krasnopeeva, Ekaterina
    Dataset supporting figures 2D, 3D and 4D of the paper "Single-cell bacterial electrophysiology reveals mechanisms of stress induced damage" (Krasnopeeva et al, 2018). The archive contains excel spreadsheets with the data ...
  • Lamin A conformation modelling 

    Houston, Douglas R; Makarov, Alex A; Zou, Juan; Spanos, Christos; Solovyova, Alexandra S; Cardenal-Peralta, Cristina; Rappsilber, Juri; Schirmer, Eric C
    Data in support of manuscript: "Lamin A molecular compression and sliding as mechanisms behind nucleoskeleton elasticity" Lamin A is a nuclear intermediate filament protein critical for nuclear architecture and mechanics ...
  • Hfq CLASH and TEX processed data 

    Granneman, Sander
    The data contains bedgraph and GTF annotation files that were used for the Iosub et al paper describing Hfq CLASH data. Included as well are test files that will allow users to learn how to use the Granneman Lab GenomeBrowser ...
  • Photometric stereo test data set 

    McCormick, Alistair; Scorza, Livia; Bernotas, Gytis
    A test data set for extracting trait data from Arabidopsis thaliana plants using PS-Plant software. The data set included raw and processed data, and a pre-trained Mask R-CNN model. This data set forms part of work done ...
  • Photometric stereo training data set with annotated leaf masks 

    Scorza, Livia; Bernotas, Gytis; McCormick, Alistair
    Automated leaf segmentation is a challenging area in computer vision. Recent advances in machine learning approaches allowed to achieve better results than traditional image processing techniques; however, training such ...

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