Royal (Dick) School of Veterinary Studies
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The Royal (Dick) School of Veterinary Studies is a world leader in veterinary education, research, and clinical practice.
Our mission is to benefit society and the environment by educating veterinary surgeons to become members of world-wide public and professional health care teams; and to advance veterinary and comparative medicine through research into disease and disease processes with the goal of improving the health and welfare of both animals and human beings.
We provide outstanding veterinary education at both undergraduate and postgraduate level, using an award winning curriculum, innovative teaching methods, and an interdisciplinary environment, for both our undergraduate and postgraduate students. Along with the Roslin Institute, which is incorporated with the School, our research spans all aspects of veterinary medicine, from molecules and genes through to animal and human populations. We aim to make a real difference through research which is directly relevant to the improvement of health and welfare of domestic animal species and the protection of public health.
Image: Detail from "D690.JPG Head of adult mute swan" from Pennycott, Tom. (2016). Swans. Images of pathology (miscellaneous diseases)., 1994-2013 [image]. University of Edinburgh. Royal (Dick) School of Veterinary Studies. https://doi.org/10.7488/ds/1567.
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Dogslife
Canine morphology, lifestyle and illness survey
Recent Submissions
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lentiviral mediated apoE4 transduction in primary neuronal culture
To identify the molecular changes in signalling pathways triggered by altered apoE4 expression, we used lentiviral transduction to overexpress human apoE4 in 18-21 DIV primary hippocampal neurons. The molecular consequences ... -
2020_Thesis_SupplementaryData_s1569052_Tissue-resident immune cells in health and disease: their heterogeneity and associated gene signatures
The dataset includes supplementary figures and tables in support of the University of Edinburgh thesis titled "Tissue-resident immune cells in health and disease: their heterogeneity and associated gene signatures". -
Staphylococcus aureus secreted lipases do not inhibit innate immune killing mechanisms: Extended Figure 1
Staphylococcus aureus pathogenesis is mediated by a plethora of secreted proteins, many of which remain incompletely characterised. For example, S. aureus abundantly secretes two isoforms of the enzyme lipase into the ... -
XP-EHH and XP-CLR scores across water buffalo and cattle breeds
This dataset consists of XP-EHH and XP-CLR scores calculated using the hapbin (https://github.com/evotools/hapbin) and xpclr (https://github.com/hardingnj/xpclr) software with default parameters across 79 water buffalo and ... -
Gene expression in the cardiovascular system of the domestic sheep (Ovis aries)
This dataset includes gene expression estimates, from RNA-Seq, for seven cardiovascular and one skeletal muscle tissue from the sheep gene expression atlas dataset (https://journals.plos.org/plosgenetics/article?id=10.13 ... -
Characterisation of a second gain of function EDAR variant, encoding EDAR380R, in East Asia
Bash scripts, R scripts, rehh output data. -
A comparison of livestock movement network-methods and implications for disease control in developing countries
The use of network analysis to support livestock disease control in low middle-income countries (LMICs) has historically been hampered by the cost of generating empirical data in the absence of animal movement recording ... -
The Infectious Diseases of East African Livestock (IDEAL) Project Database - Stable Snapshot
The Infectious Diseases of East African Livestock (IDEAL) project was a longitudinal cohort study of calf health which was conducted in Western Kenya between 2007-2009. It collected information on 548 East African shorthorn ... -
CKCS CEL data
The dataset is microrarray data collected from canine RNA samples. The experimental design of this project is to perform comparative analysis (unpaired one-way ANOVA) between normal canine mitral valves, late stage Myxomatous ... -
Comparative profiling of murine CLN1 Thalamus and Cortex at early and late disease timepoints
CLN1 disease or Infantile neuronal ceroid lipofuscinosis is a fatal inherited neurodegenerative lysosomal storage disease of early childhood with no currently available therapy. CLN1 disease is caused by mutations in the ... -
Construction of OOEP_IVT, OOEP_CAG, OOEP_VASA and ROSA26_gRNAs plasmids
These pdf files outline the construction of the four CRISPR/Cas9 gene drive DNA plasmid constructs developed during Gus McFarlane's PhD (2016 to 2020). These files provide important supplementary information to his PhD ... -
Data for "Pathogen transmission from vaccinated hosts can cause dose-dependent reduction in virulence"
# Abstract # Many livestock and increasingly human vaccines are leaky, blocking symptoms without preventing infection or onward transmission. Leakiness is concerning as it increases vaccination coverage required to ... -
A putative genomic map for resistance of Bos indicus cattle in Cameroon to bovine tuberculosis
Bovine Tuberculosis (bTB) caused by Mycobacterium bovis is a livestock disease of global economic and public health importance. There are currently no effective vaccines available for livestock and so control relies on ... -
SUPERSEDED - Water buffalo and cattle XPEHH scores across breeds
## SUPERSEDED - This dataset has been replaced by the one which can be found at https://doi.org/10.7488/ds/2849 . ## This dataset consists of XP-EHH scores calculated using the hapbin software (https://github.com/evotools/hapbin) ... -
Single cell transcriptional profiling of rat embryonic stem cells defined by Rex1-EGFP reporter expression
Rat embryonic stem cells exhibit basal levels of spontaneous differentiation in 2i+LIF (2iL) culture. Expression of a stem cell specific Rex1-EGFP knock-in reporter transgene in rat ESCs was used to isolate functionally ... -
Metagenome assembled rumen-uncultured genomes (RUGs)
DNA was sequenced from rumen contents from cattle, sheep, red deer and reindeer. We constructed 391 metagenome assembled rumen-uncultured genomes (RUGs). -
An eQTL in the cystathionine beta synthase gene is linked to osteoporosis in laying hens
"An eQTL in the cystathionine beta synthase gene is linked to osteoporosis in laying hens" Dirk-Jan De Koning, Nazaret Dominguez-Gasca, Robert H. Fleming, Andrew Gill, Dominic Kurian, Andrew Law, Heather A. McCormack, ... -
Variant discovery from whole genome sequence data from a commercial broiler line and a CSFIR- mApple reporter transgenic layer line
The data comprises variants calls from whole genome sequencing (WGS) data from a set of founder broilers (n=10) and transgenic layers (n=10). The broiler samples belong to commercial Ross 308 founder population and were ... -
Unnormalised raw count estimates for the sheep gene expression atlas dataset
This dataset contains the estimated unnormalised raw counts generated using Kallisto for all RNA-Seq libraries included in the sheep gene expression atlas. ## Format ## The plain text file contains 1,954 rows of ... -
Cow genotypes before quality control in PLINK format. Dataset pertains to manuscript "Quantitative trait loci mapping for lameness associated phenotypes in Holstein Friesian dairy cattle"
Cow genotypes in PLINK format before quality control used for a GWAS study of lameness associated phenotypes in Holstein Friesian dairy cattle. Genotypes were merged from Affymetrix and Illumina SNP chips.
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