Keighren, Margaret A.; Flockhart, Jean H.; West, John D.. (2016). GPI null mouse chimaera data_Biology Open paper 2016, [dataset]. University of Edinburgh: Edinburgh Medical School: Clinical Sciences. https://doi.org/10.7488/ds/1431.
The data are numerical data used to produce Figs. 3, 6 and 7 in Keighren MA, Flockhart JH and West JD, 2016 Survival of glucose phosphate isomerase null somatic cells and germ cells in adult mouse chimaeras. Biology Open 5, 596-610. Doi 10.1242/bio.017111.
Experiments involved production and analysis of Gpi1-/-↔Gpi1c/c mouse chimaeras. Some homozygous Gpi1-/- null somatic cells, lacking the glycolytic enzyme, glucose phosphate isomerase, survived in mouse chimaeras. Breeding experiments showed that some GPI-null oocytes and spermatozoa were viable and functional.
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