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Depositordc.contributorKlaric, Lucija
Funderdc.contributor.otherMRC - Medical Research Councilen_UK
Data Creatordc.creatorHuffman, Jennifer
Data Creatordc.creatorHayward, Caroline
Date Accessioneddc.date.accessioned2016-04-12T13:48:16Z
Date Availabledc.date.available2016-04-12T13:48:16Z
Citationdc.identifier.citationHuffman, Jennifer; Hayward, Caroline. (2016). Dataset pertaining to the publication “Loci Associated with N-Glycosylation of Human Immunoglobulin G Show Pleiotropy with Autoimmune Diseases and Haematological Cancers”, [dataset]. University of Edinburgh. Institute of Genetics and Molecular Medicine.. https://doi.org/10.7488/ds/1370.en
Persistent Identifierdc.identifier.urihttp://hdl.handle.net/10283/1958
Persistent Identifierdc.identifier.urihttps://doi.org/10.7488/ds/1370
Dataset Description (abstract)dc.description.abstractDataset pertaining to the publication “Loci Associated with N-Glycosylation of Human Immunoglobulin G Show Pleiotropy with Autoimmune Diseases and Haematological Cancers”. The files are comma separated and contain genome wide association meta-analysis data for the discovery studies. Summary data are given for the meta-analyses of over 2 million directly genotyped or imputed single variant polymorphisms corresponding to the HAPMAP2 release 22 reference panel : allele2, effallele, allele for which effect (beta) is reported, allele1, alternate allele. chromosome and position are position of the SNP on NCBI36/hg18 build. Meta-analysis mean effect size (beta) is the inverse-variance weighted estimate derived from individual discovery study; sebeta is its standard error. p is meta-analysis P-value; npops is the number of populations used for meta-analysis at that locus; n is the total number of samples used in individual level GWASs. Meta-analysis estimates are corrected for inflation of test statistics using genomic control at the individual study level. The archive IgGGlycans_GWAMA_2013.tar.gz contains seventy-seven gzipped files corresponding to genome-wide association meta-analysis (GWAMA) of seventy-seven IgG glycans traits.en_UK
Dataset Description (TOC)dc.description.tableofcontentsThe archive IgGGlycans_GWAMA_2013.tar.gz contains seventy-seven gzipped files corresponding to genome-wide association meta-analysis (GWAMA) of seventy-seven IgG glycans traits.en_UK
Languagedc.language.isoengen_UK
Publisherdc.publisherUniversity of Edinburgh. Institute of Genetics and Molecular Medicine.en_UK
Relation (Is Referenced By)dc.relation.isreferencedbyhttps://doi.org/10.1371/journal.pgen.1003225en_UK
Relation (Is Referenced By)dc.relation.isreferencedbyLauc G, Huffman JE, Pučić M, Zgaga L, Adamczyk B, Mužinić A, et al. (2013) Loci Associated with N-Glycosylation of Human Immunoglobulin G Show Pleiotropy with Autoimmune Diseases and Haematological Cancers. PLoS Genet 9(1): e1003225. doi:10.1371/journal.pgen.1003225en_UK
Rightsdc.rightsCreative Commons Attribution 4.0 International Public Licenseen
Subjectdc.subjectGenome-wide association studyen_UK
Subjectdc.subjectGlycosylationen_UK
Subjectdc.subjectGenetic locien_UK
Subjectdc.subjectSystemic lupus erythematosusen_UK
Subjectdc.subjectMeta-analysisen_UK
Subjectdc.subjectPlasma proteinsen_UK
Subjectdc.subjectBiomarkersen_UK
Subjectdc.subjectMultiple sclerosisen_UK
Subject Classificationdc.subject.classificationBiological Sciences::Medical Geneticsen_UK
Titledc.titleDataset pertaining to the publication “Loci Associated with N-Glycosylation of Human Immunoglobulin G Show Pleiotropy with Autoimmune Diseases and Haematological Cancers”en_UK
Typedc.typedataseten_UK

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