The lab's main question... how does complex biological form develop from simple beginnings? This is tackled this by a combination of the following:
- Studying normal development (especially of internal organs)
- Tissue engineering of organs from stem and other progenitor cells
- Synthetic morphology (engineering naive cells to do build designed entities)
- Computer modelling to test ideas and to inform experiments
- Running two international databases, as a service to the wider field
- Sharing the wonders of development with university students and the public
Items in this Collection
Data supporting Cachat et al. (2017): "Synthetic self-patterning and morphogenesis in mammalian cells: a proof-of-concept step towards synthetic tissue development" These are raw image datasets used in a manuscript (Cachat et al., 2017: Synthetic self-patterning and morphogenesis in mammalian cells: a proof-of-concept step towards synthetic tissue development) with the following ...
These are raw image datasets and analyses used in a J. Anat. paper (Martin et al., 2017) with the following abstract: Branching morphogenesis of epithelia involves division of cells into leader (tip) and follower (stalk) ...